Pub. Date : 2020
PMID : 33024416
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The purpose of the present study was to investigate the possible role of LINC00961 in luminal A and B subtypes of BC. | Phenobarbital | small regulatory polypeptide of amino acid response | Homo sapiens |
2 | After performing literature review, the expression level of the selected lncRNA (LINC00961) was evaluated in 79 luminal A and B BC specimens and adjacent non-cancerous tissues by Quantitative Reverse Transcription PCR (qRT-PCR). | Phenobarbital | small regulatory polypeptide of amino acid response | Homo sapiens |
3 | According to q-RT PCR assay, LINC00961 was downregulated in luminal BC tissues and cell lines. | Phenobarbital | small regulatory polypeptide of amino acid response | Homo sapiens |
4 | The final results indicated that LINC00961 might be involved in multiple cancer-associated pathways such as chemokine, Ras and PI3K-Akt signaling pathways, GPCR ligand binding, and signal transduction in luminal subtypes of BC. | Phenobarbital | small regulatory polypeptide of amino acid response | Homo sapiens |
5 | Conclusion: Our findings suggested that LINC00961 was significantly downregulated in luminal A and B subtypes of BC. | Phenobarbital | small regulatory polypeptide of amino acid response | Homo sapiens |
6 | Moreover, bioinformatics analysis provided a basis for better identification of the potential role of LINC00961 in luminal subtype of BC. | Phenobarbital | small regulatory polypeptide of amino acid response | Homo sapiens |