Title : The Bioassay-Guided Fractionation and Identification of Potent Acetylcholinesterase Inhibitors from Narcissus c.v. 'Hawera' Using Optimized Vacuum Liquid Chromatography, High Resolution Mass Spectrometry and Bioautography.

Pub. Date : 2020 Oct 4

PMID : 33020380






3 Functional Relationships(s)
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1 The aim of this paper was to fractionate and isolate alkaloids by developing an innovative vacuum liquid chromatography method for a species of Narcissus c.v. "Hawera" rarely investigated so far and establishing the inhibitory activity of acetylcholinesterase (AChE). Alkaloids acetylcholinesterase (Cartwright blood group) Homo sapiens
2 The aim of this paper was to fractionate and isolate alkaloids by developing an innovative vacuum liquid chromatography method for a species of Narcissus c.v. "Hawera" rarely investigated so far and establishing the inhibitory activity of acetylcholinesterase (AChE). Alkaloids acetylcholinesterase (Cartwright blood group) Homo sapiens
3 The combination of these techniques confirmed the presence of the alkaloids and enabled the development of a modern method for the fractionation and isolation of the compounds with strong anti-AChE activity. Alkaloids acetylcholinesterase (Cartwright blood group) Homo sapiens