Title : Adipokines as a therapeutic target by metformin to improve metabolic function: A systematic review of randomized controlled trials.

Pub. Date : 2021 Jan

PMID : 33017649






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1 Cumulative evidence from these RCTs supported the blood glucose lowering effects of metformin, in addition to promoting weight loss, ameliorating insulin resistance, and reducing pro-inflammatory markers such as interleukin-6 and tumor necrosis factor-alpha in patients with metabolic syndrome. Metformin interleukin 6 Homo sapiens