Title : Characterization of five novel vasopressin V2 receptor mutants causing nephrogenic diabetes insipidus reveals a role of tolvaptan for M272R-V2R mutation.

Pub. Date : 2020 Oct 2

PMID : 33009446






1 Functional Relationships(s)
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1 These results show an important proof of concept for the use of tolvaptan in patients affected by M272R mutation of V2R causing NDI. Tolvaptan arginine vasopressin receptor 2 Homo sapiens