Title : Design, synthesis, and multitargeted profiling of N-benzylpyrrolidine derivatives for the treatment of Alzheimer's disease.

Pub. Date : 2020 Nov 15

PMID : 33007563






1 Functional Relationships(s)
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1 In silico molecular docking and dynamics simulation studies of leads suggested their consensual binding affinity toward PAS-AChE in addition to aspartate dyad of BACE-1. Aspartic Acid beta-secretase 1 Homo sapiens