Title : Application of a plasmin generation assay to define pharmacodynamic effects of tranexamic acid in women undergoing cesarean delivery.

Pub. Date : 2021 Jan

PMID : 33001565






3 Functional Relationships(s)
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Protein Name
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1 Application of a plasmin generation assay to define pharmacodynamic effects of tranexamic acid in women undergoing cesarean delivery. Tranexamic Acid plasminogen Homo sapiens
2 TXA inhibits plasmin(ogen) binding to fibrin and reduces fibrinolysis. Tranexamic Acid plasminogen Homo sapiens
3 For all doses of TXA administered intravenously, the PG assay detected delayed time-to-peak (<=3 hours) and reduced the velocity, peak, and endogenous plasmin potential (<=24 hours) in plasma samples obtained post-infusion. Tranexamic Acid plasminogen Homo sapiens