Title : Icariin modulates the sirtuin/NF‑κB pathway and exerts anti‑aging effects in human lung fibroblasts.

Pub. Date : 2020 Nov

PMID : 33000191






1 Functional Relationships(s)
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1 Furthermore, it was also demonstrated that the activation of p53/p21 and nuclear factor-kappaB (NF-kappaB) signaling, and downregulation of SIRT1/6 may be involved in IMR-90 cells, in D-gal-induced aging and ICA may effectively prevent IMR-90 cells from these changes induced by D-gal. Galactose tumor protein p53 Homo sapiens