Pub. Date : 2020 Oct
PMID : 32990902
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | VD3 and LXR agonist (T0901317) combination demonstrated greater potency in inhibiting cholesterol accumulation and inducing apoptosis via ABCA1-CHOP-BCL-2 cascade in MCF-7 breast cancer cells. | T0901317 | DNA damage inducible transcript 3 | Homo sapiens |
2 | Importantly, VD3 + T0901317 combination showed higher effects in increasing apoptosis as measured by annexin apoptosis assay, cell viability and was associated with induction of CHOP protein and gene expression. | T0901317 | DNA damage inducible transcript 3 | Homo sapiens |