Title : The Role of Sirtuin-1 in the Vasculature: Focus on Aortic Aneurysm.

Pub. Date : 2020

PMID : 32982786






1 Functional Relationships(s)
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1 HO-1 and HO-2 catalyze the rate-limiting step of cellular heme degradation and, similar to SirT1, HO-1 exerts beneficial effects in the vasculature through the activation of anti-oxidant, anti-inflammatory, anti-apoptotic, and anti-proliferative signaling pathways. Heme heme oxygenase 1 Homo sapiens