Title : Exploding the Repeat Length Paradigm while Exploring Amyloid Toxicity in Huntington's Disease.

Pub. Date : 2020 Oct 20

PMID : 32975927






5 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 ConspectusHuntington"s disease (HD) is a progressive, familial neurodegenerative disease triggered by the expansion of a polyglutamine (polyQ) track in the protein huntingtin (htt). polyglutamine huntingtin Rattus norvegicus
2 ConspectusHuntington"s disease (HD) is a progressive, familial neurodegenerative disease triggered by the expansion of a polyglutamine (polyQ) track in the protein huntingtin (htt). polyglutamine huntingtin Rattus norvegicus
3 ConspectusHuntington"s disease (HD) is a progressive, familial neurodegenerative disease triggered by the expansion of a polyglutamine (polyQ) track in the protein huntingtin (htt). polyglutamine huntingtin Rattus norvegicus
4 ConspectusHuntington"s disease (HD) is a progressive, familial neurodegenerative disease triggered by the expansion of a polyglutamine (polyQ) track in the protein huntingtin (htt). polyglutamine huntingtin Rattus norvegicus
5 PolyQ sequences up to Q36 in htt are not known to be toxic, while polyQ lengths above Q36 almost invariably lead to increased disease risk and decreased ages of onset. polyglutamine huntingtin Rattus norvegicus