Title : Heme oxygenase 1 protects human colonocytes against ROS formation, oxidative DNA damage and cytotoxicity induced by heme iron, but not inorganic iron.

Pub. Date : 2020 Sep 23

PMID : 32968051






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Heme oxygenase 1 protects human colonocytes against ROS formation, oxidative DNA damage and cytotoxicity induced by heme iron, but not inorganic iron. Heme heme oxygenase 1 Homo sapiens
2 Furthermore, HO-1 abrogation strongly augmented the cytotoxic effects of hemin in HCEC, revealing its pivotal function in colonocytes and highlighting the toxicity of free intracellular heme iron. Heme heme oxygenase 1 Homo sapiens