Title : Repurposing of the PDE5 Inhibitor Sildenafil for the Treatment of Persistent Pulmonary Hypertension in Neonates.

Pub. Date : 2021

PMID : 32964819






3 Functional Relationships(s)
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1 Repurposing of the PDE5 inhibitor sildenafil for treatment of persistent pulmonary hypertension in neonates. Sildenafil Citrate phosphodiesterase 5A Homo sapiens
2 Small molecule PDE5 inhibitors (PDE5is) such as sildenafil prolong the availability of cGMP and so enhance NO-mediated signalling. Sildenafil Citrate phosphodiesterase 5A Homo sapiens
3 Small molecule PDE5 inhibitors (PDE5is) such as sildenafil prolong the availability of cGMP and so enhance NO-mediated signalling. Sildenafil Citrate phosphodiesterase 5A Homo sapiens