Title : Estrogen signaling differentially alters iron metabolism in monocytes in an Interleukin 6-dependent manner.

Pub. Date : 2020 Sep

PMID : 32962815






1 Functional Relationships(s)
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1 While treatment of U937 cells with interleukin 6 (IL-6) resulted in increased expression of hepcidin, dexamethasone treatment resulted in reduced hepcidin synthesis relative to E2- or dexamethasone + E2-treated cells; IL-6 silencing also resulted in reduced hepcidin synthesis in U937 cells. Dexamethasone interleukin 6 Homo sapiens