Title : Hypoxia induces the translocation of glucose transporter 1 to the plasma membrane in vascular endothelial cells.

Pub. Date : 2020 Sep 22

PMID : 32962633






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 GLUT1 translocation was associated with a decrease of intracellular ATP by hypoxia. Adenosine Triphosphate solute carrier family 2 member 1 Homo sapiens
2 Decreasing ATP levels with antimycin-A and 2-deoxyglucose induced GLUT1 translocation under normoxia. Adenosine Triphosphate solute carrier family 2 member 1 Homo sapiens
3 These observations indicate that a decrease of intracellular ATP triggers GLUT1 translocation to the plasma membrane and is mediated by KATP channels, which would contribute to glucose uptake in HUVECs during hypoxia. Adenosine Triphosphate solute carrier family 2 member 1 Homo sapiens