Pub. Date : 2020 Dec
PMID : 32959891
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | KEY RESULTS: Apical application of the nAChR agonist nicotine transiently increased ISC (EC50 : 19.83 mumol*L-1 ). | Nicotine | cholinergic receptor, nicotinic, alpha polypeptide 7 | Mus musculus |
2 | The nicotine-effect was abolished by the nAChR inhibitor mecamylamine. | Nicotine | cholinergic receptor, nicotinic, alpha polypeptide 7 | Mus musculus |
3 | CONCLUSIONS AND IMPLICATIONS: alpha3beta4 nAChR are responsible for the nicotine-induced current changes via Ca2+ -release from intracellular stores, PKA and ryanodine receptor activation. | Nicotine | cholinergic receptor, nicotinic, alpha polypeptide 7 | Mus musculus |