Title : A Cyclic Phosphoramidate Prodrug of 2'-Deoxy-2'-Fluoro-2'-C-Methylguanosine for the Treatment of Dengue Virus Infection.

Pub. Date : 2020 Nov 17

PMID : 32958712






1 Functional Relationships(s)
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1 At 100 mg/kg BID, the terminal triphosphate concentration in PBMCs reached above TP50, demonstrating TP50 as the target exposure for efficacy. triphosphoric acid BH3 interacting domain death agonist Mus musculus