Title : β-Hydroxybutyrate inhibits inflammasome activation to attenuate Alzheimer's disease pathology.

Pub. Date : 2020 Sep 21

PMID : 32958021






2 Functional Relationships(s)
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1 Therefore, we tested if BHB inhibition of the NLRP3 inflammasome reduces overall AD pathology in the 5XFAD mouse model of AD. 3-Hydroxybutyric Acid NLR family, pyrin domain containing 3 Mus musculus
2 Taken together, our findings demonstrate that BHB reduces AD pathology by inhibiting NLRP3 inflammasome activation. 3-Hydroxybutyric Acid NLR family, pyrin domain containing 3 Mus musculus