Pub. Date : 2020 Sep 11
PMID : 32953930
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In addition, SIS3 treatment also halted the progression of myocardial fibrosis by blocking alpha-smooth muscle actin-positive (alpha-SMA+) myofibroblasts and collagen matrix accumulation, and inhibited cardiac inflammation by suppressing interleukin (IL)-1beta, tumor necrosis factor alpha (TNF-alpha), monocyte chemotactic protein 1 (MCP1), intercellular cell adhesion molecule-1 (ICAM1) expression, and infiltration of CD3+ T cells and F4/80+ macrophages. | 6,7-dimethyl-2-(2E)-3-(1-methyl-2-phenyl-1H-pyrrolo(2,3-b)pyridin-3-yl-prop-2-enoyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride | actin alpha 2, smooth muscle, aorta | Mus musculus |