Title : New insights on the arylpiperazinylalkyl pyridazinone ET1 as potent antinociceptive and anti-inflammatory agent.

Pub. Date : 2020 Dec 5

PMID : 32946866






1 Functional Relationships(s)
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1 Binding experiments confirmed an inhibitory effect on adrenergic alpha1A, alpha1B and alpha2A receptors subtypes and, for the first time, a moderate affinity was observed for the following receptors: histamine H1, imidazoline I2, sigma non-opioid intracellular receptor 1 and sigma2. Histamine adrenergic receptor, alpha 2a Mus musculus