Title : Neuroinflammatory inhibition of synaptic long-term potentiation requires immunometabolic reprogramming of microglia.

Pub. Date : 2021 Mar

PMID : 32946147






1 Functional Relationships(s)
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1 Remarkably, the addition of 2DG to blunt the microglial glycolytic increase also inhibited HIF-1alpha accumulation and IL-1beta production, and therefore rescued LTP in LPS-stimulated slices. Deoxyglucose interleukin 1 alpha Homo sapiens