Title : CDK9 activity is critical for maintaining MDM4 overexpression in tumor cells.

Pub. Date : 2020 Sep 15

PMID : 32934219






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 CDK9 inhibitor atuveciclib downregulated MDM4 and enhanced p53 activity induced by nutlin-3a, an inhibitor of p53-MDM2 interaction, and synergized with nutlin-3a in killing A375 melanoma cells. nutlin 3 tumor protein p53 Homo sapiens
2 CDK9 inhibitor atuveciclib downregulated MDM4 and enhanced p53 activity induced by nutlin-3a, an inhibitor of p53-MDM2 interaction, and synergized with nutlin-3a in killing A375 melanoma cells. nutlin 3 tumor protein p53 Homo sapiens