Title : Disease mechanism, biomarker and therapeutics for spinal and bulbar muscular atrophy (SBMA).

Pub. Date : 2020 Oct

PMID : 32934110






1 Functional Relationships(s)
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1 Androgen-dependent nuclear accumulation of the polyglutamine-expanded AR is an essential step in the pathogenesis, providing therapeutic opportunities via hormonal manipulation and gene silencing with antisense oligonucleotides. polyglutamine androgen receptor Homo sapiens