Title : Cathepsin Inhibition Modulates Metabolism and Polarization of Tumor-Associated Macrophages.

Pub. Date : 2020 Sep 10

PMID : 32927704






2 Functional Relationships(s)
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1 The altered fatty acid profile was associated with an increased synthesis of the pro-inflammatory prostaglandin PGE2, which correlated with the upregulation of numerous NFkB-dependent pro-inflammatory mediators, including interleukin-1 (IL-1), interleukin-6 (IL-6), C-C motif chemokine ligand 2 (CCL2), and tumor necrosis factor-alpha (TNFalpha). Dinoprostone C-C motif chemokine ligand 2 Homo sapiens
2 The altered fatty acid profile was associated with an increased synthesis of the pro-inflammatory prostaglandin PGE2, which correlated with the upregulation of numerous NFkB-dependent pro-inflammatory mediators, including interleukin-1 (IL-1), interleukin-6 (IL-6), C-C motif chemokine ligand 2 (CCL2), and tumor necrosis factor-alpha (TNFalpha). Dinoprostone C-C motif chemokine ligand 2 Homo sapiens