Pub. Date : 2020
PMID : 32922544
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Moreover, surfactin could reduce Akt, mTOR, p65, and c-Jun activation and IL-6 secretion induced by PM. | surfactin peptide | Jun proto-oncogene, AP-1 transcription factor subunit | Homo sapiens |
| 2 | Taken together, these results suggest that surfactin functions as a suppressor of PM-induced MMP2/9-dependent oral cancer cell migration and invasion by inhibiting the activation of phosphoinositide 3-kinase (PI3K)/Akt/mTOR and PI3K/Akt/nuclear factor-kappaB (NF-kappaB) and activator protein-1 (AP-1)/IL-6 signaling pathways. | surfactin peptide | Jun proto-oncogene, AP-1 transcription factor subunit | Homo sapiens |
| 3 | Taken together, these results suggest that surfactin functions as a suppressor of PM-induced MMP2/9-dependent oral cancer cell migration and invasion by inhibiting the activation of phosphoinositide 3-kinase (PI3K)/Akt/mTOR and PI3K/Akt/nuclear factor-kappaB (NF-kappaB) and activator protein-1 (AP-1)/IL-6 signaling pathways. | surfactin peptide | Jun proto-oncogene, AP-1 transcription factor subunit | Homo sapiens |