Pub. Date : 2020 Nov
PMID : 32905825
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | 4-Aminobiphenyl suppresses homologous recombination repair by a reactive oxygen species-dependent p53/miR-513a-5p/p53 loop. | Reactive Oxygen Species | tumor protein p53 | Homo sapiens |
| 2 | 4-Aminobiphenyl suppresses homologous recombination repair by a reactive oxygen species-dependent p53/miR-513a-5p/p53 loop. | Reactive Oxygen Species | tumor protein p53 | Homo sapiens |
| 3 | On the other hand, the levels of p53, miR-513a-5p, and gammaH2AX were attenuated by 5 mM N-acetyl-l-cysteine (NAC) pretreatment, indicating that the reactive oxygen species (ROS)-dependent p53-miR-513a-5p was involved in DSB repair in 4-ABP-treated cells. | Reactive Oxygen Species | tumor protein p53 | Homo sapiens |
| 4 | On the other hand, the levels of p53, miR-513a-5p, and gammaH2AX were attenuated by 5 mM N-acetyl-l-cysteine (NAC) pretreatment, indicating that the reactive oxygen species (ROS)-dependent p53-miR-513a-5p was involved in DSB repair in 4-ABP-treated cells. | Reactive Oxygen Species | tumor protein p53 | Homo sapiens |
| 5 | On the other hand, the levels of p53, miR-513a-5p, and gammaH2AX were attenuated by 5 mM N-acetyl-l-cysteine (NAC) pretreatment, indicating that the reactive oxygen species (ROS)-dependent p53-miR-513a-5p was involved in DSB repair in 4-ABP-treated cells. | Reactive Oxygen Species | tumor protein p53 | Homo sapiens |
| 6 | These findings indicated that the ROS/p53/miR-513a-5p/p53 loop axis plays a relevant role in regulating HR repair which may facilitate our understanding of molecular mechanisms regarding how miR-513a-5p impacts DSB repair in 4-ABP-treated cells. | Reactive Oxygen Species | tumor protein p53 | Homo sapiens |
| 7 | These findings indicated that the ROS/p53/miR-513a-5p/p53 loop axis plays a relevant role in regulating HR repair which may facilitate our understanding of molecular mechanisms regarding how miR-513a-5p impacts DSB repair in 4-ABP-treated cells. | Reactive Oxygen Species | tumor protein p53 | Homo sapiens |