Title : Increased Risk of Clopidogrel-Induced Gastric Mucosal Erosion in Elderly Chinese Men Harboring the ABCB1 3435T Allele.

Pub. Date : 2020

PMID : 32904459






5 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Increased Risk of Clopidogrel-Induced Gastric Mucosal Erosion in Elderly Chinese Men Harboring the ABCB1 3435T Allele. Clopidogrel ATP binding cassette subfamily B member 1 Homo sapiens
2 This study aimed to evaluate the relationship between ABCB1 C3435T polymorphisms, which could affect the intestinal absorption of clopidogrel, and gastric mucosal erosion in elderly Chinese men who used clopidogrel alone. Clopidogrel ATP binding cassette subfamily B member 1 Homo sapiens
3 This study aimed to evaluate the relationship between ABCB1 C3435T polymorphisms, which could affect the intestinal absorption of clopidogrel, and gastric mucosal erosion in elderly Chinese men who used clopidogrel alone. Clopidogrel ATP binding cassette subfamily B member 1 Homo sapiens
4 After adjustments for significant factors were made, ABCB1 3435T allele carrier (OR 2.14, 95% CI 1.43-3.84, p <0.01) was found to be associated with gastric mucosal erosion in people who used clopidogrel alone. Clopidogrel ATP binding cassette subfamily B member 1 Homo sapiens
5 Conclusion: Carrying the ABCB1 3435T allele may be a useful genetic predictor for clopidogrel-induced gastric mucosal erosion in elderly Chinese men. Clopidogrel ATP binding cassette subfamily B member 1 Homo sapiens