Title : TOPK inhibition accelerates oxidative stress‑induced granulosa cell apoptosis via the p53/SIRT1 axis.

Pub. Date : 2020 Nov

PMID : 32901866






1 Functional Relationships(s)
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1 Furthermore, the p53 inhibitor, Pifithrin-mu, diminished the augmentation in poly(ADP-ribose) polymerase (PARP) cleavage induced by OTS514 plus H2O2, while the Mdm2 antagonist, Nutlin 3, increased PARP cleavage. pifithrin tumor protein p53 Homo sapiens