Title : Low‑dose trametinib and Bcl‑xL antagonist have a specific antitumor effect in KRAS‑mutated colorectal cancer cells.

Pub. Date : 2020 Nov

PMID : 32901840






1 Functional Relationships(s)
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1 A drug-screening system (Mix Culture assay) was then applied, revealing that the cells were most sensitive to the MEK inhibitor trametinib among tested drugs, Cetuximab, Panitumumab, Regorafenib, Vemurafenib, BEZ-235 and Palbociclib. regorafenib mitogen-activated protein kinase kinase 7 Homo sapiens