Pub. Date : 2020 Nov
PMID : 32901836
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Calycosin induces apoptosis via p38-MAPK pathway-mediated activation of the mitochondrial apoptotic pathway in human osteosarcoma 143B cells. | 7,3'-dihydroxy-4'-methoxyisoflavone | mitogen-activated protein kinase 14 | Homo sapiens |
| 2 | Calycosin induces apoptosis via p38-MAPK pathway-mediated activation of the mitochondrial apoptotic pathway in human osteosarcoma 143B cells. | 7,3'-dihydroxy-4'-methoxyisoflavone | mitogen-activated protein kinase 14 | Homo sapiens |
| 3 | Furthermore, calycosin treatment induced p38-mitogen-activated protein kinase (MAPK) phosphorylation, whereas the p38-MAPK inhibitor BIRB 796 markedly reversed cell viability, apoptosis and loss of MMP in 143B cells. | 7,3'-dihydroxy-4'-methoxyisoflavone | mitogen-activated protein kinase 14 | Homo sapiens |
| 4 | Furthermore, calycosin treatment induced p38-mitogen-activated protein kinase (MAPK) phosphorylation, whereas the p38-MAPK inhibitor BIRB 796 markedly reversed cell viability, apoptosis and loss of MMP in 143B cells. | 7,3'-dihydroxy-4'-methoxyisoflavone | mitogen-activated protein kinase 14 | Homo sapiens |
| 5 | These results suggested that calycosin inhibited osteosarcoma 143B cell growth via p38-MAPK regulation of mitochondrial-dependent intrinsic apoptotic pathways. | 7,3'-dihydroxy-4'-methoxyisoflavone | mitogen-activated protein kinase 14 | Homo sapiens |
| 6 | These results suggested that calycosin inhibited osteosarcoma 143B cell growth via p38-MAPK regulation of mitochondrial-dependent intrinsic apoptotic pathways. | 7,3'-dihydroxy-4'-methoxyisoflavone | mitogen-activated protein kinase 14 | Homo sapiens |