Pub. Date : 2020 Nov 19
PMID : 32900490
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Glycyrrhetinic acid alleviates acute lung injury by PI3K/AKT suppressing macrophagic Nlrp3 inflammasome activation. | Glycyrrhetinic Acid | thymoma viral proto-oncogene 1 | Mus musculus |
| 2 | Furthermore, GA downregulated the production of reactive oxygen species (ROS) and the phosphorylation level of PI3K and AKT in macrophages. | Glycyrrhetinic Acid | thymoma viral proto-oncogene 1 | Mus musculus |
| 3 | These findings indicate that GA ameliorated ALI in mice by suppressing the activation of Nlrp3 inflammasome which may be mediated by ROS-PI3K/AKT pathway. | Glycyrrhetinic Acid | thymoma viral proto-oncogene 1 | Mus musculus |