Pub. Date : 2020 Sep 3
PMID : 32899436
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The Role of Thiocyanate in Modulating Myeloperoxidase Activity during Disease. | thiocyanate | myeloperoxidase | Homo sapiens |
2 | Thiocyanate can outcompete chlorine anions and other halides (F-, Br-, I-) as substrates for myeloperoxidase by undergoing two-electron oxidation with hydrogen peroxide. | thiocyanate | myeloperoxidase | Homo sapiens |
3 | As such, the pharmacological capacity of thiocyanate has been recently investigated for its ability to modulate myeloperoxidase activity for HOSCN, a less potent species relative to HOCl, although outcomes vary significantly across different disease models. | thiocyanate | myeloperoxidase | Homo sapiens |