Title : Modulation of antioxidant enzymes, SIRT1 and NF-κB by resveratrol and nicotinamide in alcohol-aflatoxin B1-induced hepatocellular carcinoma.

Pub. Date : 2021 Jan

PMID : 32894639






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 SIRT1 agonist resveratrol was observed to modulate the activity of antioxidant enzymes by negatively regulating the expression of nuclear factor-kappaB (NF-kappaB) in alcohol-aflatoxin B1-induced HCC, thereby suggesting a cross-talk between antioxidant enzymes SIRT1 and NF-kappaB during the development and progression of HCC and its therapeutics by resveratrol and nicotinamide. Niacinamide sirtuin 1 Homo sapiens