Title : Abundance of P-Glycoprotein and Other Drug Transporters at the Human Blood-Brain Barrier in Alzheimer's Disease: A Quantitative Targeted Proteomic Study.

Pub. Date : 2021 Mar

PMID : 32885413






2 Functional Relationships(s)
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1 Using PET imaging, we have shown that BBB P-gp activity is reduced in AD, as quantified by the in vivo brain distribution of the P-gp probe, [11 C]-verapamil. Verapamil ATP binding cassette subfamily B member 1 Homo sapiens
2 Using PET imaging, we have shown that BBB P-gp activity is reduced in AD, as quantified by the in vivo brain distribution of the P-gp probe, [11 C]-verapamil. Verapamil ATP binding cassette subfamily B member 1 Homo sapiens