Pub. Date : 2020 Aug 30
PMID : 32872656
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The aim of this work was to determine whether Capsaicin may exert a vascular regulation through the activation of CB1 and/or CB2 receptors causing vasorelaxation in the rat aorta. | Capsaicin | cannabinoid receptor 1 | Rattus norvegicus |
| 2 | In these experiments, we found that the inhibition of CB1 using AM281, decreases the vasorelaxant effect caused by Capsaicin. | Capsaicin | cannabinoid receptor 1 | Rattus norvegicus |
| 3 | These findings are supported by CB1 docking simulation which predicted a binding site on CB1 receptors for Capsaicin. | Capsaicin | cannabinoid receptor 1 | Rattus norvegicus |