Title : Metformin Derivative HL156A Reverses Multidrug Resistance by Inhibiting HOXC6/ERK1/2 Signaling in Multidrug-Resistant Human Cancer Cells.

Pub. Date : 2020 Aug 28

PMID : 32872293






1 Functional Relationships(s)
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1 We found that HL156A inhibited the expression of MDR1 by inhibiting the HOXC6-mediated ERK1/2 signaling pathway and increased the sensitivity to paclitaxel or doxorubicin in MDR cells. Doxorubicin ATP binding cassette subfamily B member 1 Homo sapiens