Title : Suppressing BRD4 exhibits protective effects against vincristine-induced peripheral neuropathy by alleviating inflammation and oxidative stress.

Pub. Date : 2020 Nov 5

PMID : 32868081






1 Functional Relationships(s)
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1 The in vitro studies indicated that in H2O2-stimulated primary neurons, BRD4 silence markedly reduced reactive oxygen species (ROS) production and improved Nrf-2 activation, exhibiting anti-oxidant effects. Hydrogen Peroxide nuclear factor, erythroid derived 2, like 2 Mus musculus