Pub. Date : 2020 Sep 1
PMID : 32867831
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Boswellic acid sensitizes gastric cancer cells to Cisplatin-induced apoptosis via p53-mediated pathway. | Cisplatin | tumor protein p53 | Homo sapiens |
| 2 | BACKGROUND: Cisplatin (CDDP) is an effective anticancer drug for Gastric cancer (GC) that induces apoptosis by altering pro- (p53) and anti-apoptotic (Akt and NFkB) proteins; however, chemoresistance remains a big challenge. | Cisplatin | tumor protein p53 | Homo sapiens |
| 3 | BACKGROUND: Cisplatin (CDDP) is an effective anticancer drug for Gastric cancer (GC) that induces apoptosis by altering pro- (p53) and anti-apoptotic (Akt and NFkB) proteins; however, chemoresistance remains a big challenge. | Cisplatin | tumor protein p53 | Homo sapiens |
| 4 | This study aimed to examine the effectiveness of AKBA on p53-mediated, CDDP-induced apoptosis in GC cells. | Cisplatin | tumor protein p53 | Homo sapiens |
| 5 | CONCLUSIONS: Altogether, our findings suggest that AKBA enhances GC cell sensitivity to CDDP-induced apoptosis via the p53 pathway. | Cisplatin | tumor protein p53 | Homo sapiens |