Title : Pol β gap filling, DNA ligation and substrate-product channeling during base excision repair opposite oxidized 5-methylcytosine modifications.

Pub. Date : 2020 Nov

PMID : 32853828






1 Functional Relationships(s)
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1 Here, we report that, in contrast to the pol beta mismatch insertion products (dCTP, dATP, and dTTP), the nicked products after pol beta dGTP insertion can be ligated by DNA ligase I or DNA ligase III/XRCC1 complex when a 5mC oxidation modification is present opposite in the template position in vitro. deoxyguanosine triphosphate X-ray repair cross complementing 1 Homo sapiens