Title : Molecular insights into the differential structure-dynamics-stability features of interleukin-8 orthologs: Implications to functional specificity.

Pub. Date : 2020 Dec 1

PMID : 32853623






1 Functional Relationships(s)
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1 Indeed, structural and sequence analysis evidenced for specificity of molecular interactions with cognate receptor (CXCR1) and glycosaminoglycan (heparin), thus providing evidence for a noticeable functional specificity and divergence between the two IL8 orthologs. Heparin C-X-C motif chemokine ligand 8 Homo sapiens