Pub. Date : 2021
PMID : 32851964
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Novel coumarin containing dithiocarbamate derivatives as potent alpha-glucosidase inhibitors for management of type 2 diabetes. | Dithiocarbamate | sucrase-isomaltase | Homo sapiens |
| 2 | OBJECTIVE: In this study, novel coumarin containing dithiocarbamate derivatives 4a-n were synthesized and evaluated against alpha-glucosidase in vitro and in silico. | Dithiocarbamate | sucrase-isomaltase | Homo sapiens |
| 3 | CONCLUSION: Our results suggest that the coumarin-dithiocarbamate scaffold can be a promising lead structure for design potent alpha-glucosidase inhibitors for treatment of type 2 diabetes. | Dithiocarbamate | sucrase-isomaltase | Homo sapiens |