Title : Inhibition of autophagy enhances cadmium-induced apoptosis in duck renal tubular epithelial cells.

Pub. Date : 2020 Dec 1

PMID : 32836151






2 Functional Relationships(s)
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1 Moreover, co-treatment with Cd and 3-MA could notably elevate Caspase-3, Cyt C, Bax, and Bak-1 mRNA levels, Caspase-3 and cleaved Caspase-3 protein levels, and cell apoptotic rate as well as cell damage, decreased mitochondrial membrane potential (MMP), Bcl-2 mRNA level and the ratio of Bcl-2 to Bax compared to treatment with Cd alone. 3-methyladenine BCL2 apoptosis regulator Homo sapiens
2 Moreover, co-treatment with Cd and 3-MA could notably elevate Caspase-3, Cyt C, Bax, and Bak-1 mRNA levels, Caspase-3 and cleaved Caspase-3 protein levels, and cell apoptotic rate as well as cell damage, decreased mitochondrial membrane potential (MMP), Bcl-2 mRNA level and the ratio of Bcl-2 to Bax compared to treatment with Cd alone. 3-methyladenine BCL2 apoptosis regulator Homo sapiens