Title : [The role and mechanism of leucyl-tRNA synthetase in the regulation of protein synthesis in aging skeletal muscle].

Pub. Date : 2020 Aug 25

PMID : 32820315






3 Functional Relationships(s)
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1 The canonical role of leucyl-tRNA synthetase (LeuRS) is ligating leucine to the cognate tRNA, and thus it plays a central role in genetic coding. Leucine leucyl-tRNA synthetase 1 Homo sapiens
2 The canonical role of leucyl-tRNA synthetase (LeuRS) is ligating leucine to the cognate tRNA, and thus it plays a central role in genetic coding. Leucine leucyl-tRNA synthetase 1 Homo sapiens
3 In this paper, we reviewed the structure and biological features of aminoacyl-tRNA synthetase and LeuRS, and summarized the recent advances in studies on the effects of LeuRS in regulating aging skeletal muscle protein synthesis as an intracellular leucine sensor. Leucine leucyl-tRNA synthetase 1 Homo sapiens