Title : Structural insight into the effect of polymorphic variation on the functional dynamics of methionine synthase reductase: Implications in neural tube defects.

Pub. Date : 2021 Feb

PMID : 32812692






1 Functional Relationships(s)
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1 Here, extensive molecular dynamics simulations and interaction network analysis reveal that the 49th isoleucine is a crucial residue that allosterically regulates the dynamics between the FMN and NADP(H) binding domains. NADP formin 1 Homo sapiens