Title : The therapeutic potential of colchicine in the complications of COVID19. Could the immunometabolic properties of an old and cheap drug help?

Pub. Date : 2020 Sep

PMID : 32808940






1 Functional Relationships(s)
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1 Studies show that colchicine, among other actions, inhibits the assembly of NLRP3 complex that is responsible for generating the active form of Caspase-1 that will convert Pro-IL-1beta and Pro-IL-18 into their active forms. Colchicine NLR family pyrin domain containing 3 Homo sapiens