Pub. Date : 2020 Sep
PMID : 32804466
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In this study, we tested the hypothesis that H2 alleviates oxidative stress by suppressing xanthine oxidoreductase (XOR) and/or preventing tumor necrosis factor-alfa (TNF-alpha)-mediated syndecan-1 shedding during EG damage. | Deuterium | tumor necrosis factor | Rattus norvegicus |
| 2 | H2 suppressed plasma TNF-alpha and syndecan-1 expression; however, no additional H2 therapeutic effect was observed in the presence of anti-TNF-alpha monoclonal antibody. | Deuterium | tumor necrosis factor | Rattus norvegicus |
| 3 | The therapeutic action of H2 was partially mediated by inhibition of TNF-alpha-dependent syndecan-1 shedding. | Deuterium | tumor necrosis factor | Rattus norvegicus |