Title : Quinolines-Based SARS-CoV-2 3CLpro and RdRp Inhibitors and Spike-RBD-ACE2 Inhibitor for Drug-Repurposing Against COVID-19: An in silico Analysis.

Pub. Date : 2020

PMID : 32793181






1 Functional Relationships(s)
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Protein Name
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1 Out of 113 quinoline-drugs, elvitegravir and oxolinic acid are able to interact with the NTP entry-channel and thus interfere with the RNA-directed 5"-3" polymerase activity of SARS-CoV-2 RdRp. quinoline ORF1a polyprotein;ORF1ab polyprotein Severe acute respiratory syndrome coronavirus 2