Title : The SUMO-specific protease SENP1 deSUMOylates p53 and regulates its activity.

Pub. Date : 2021 Feb

PMID : 32786121






1 Functional Relationships(s)
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1 We further show that SENP1 depletion synergizes with DNA damage-inducing agent etoposide to induce p53 activation and the expression of p21, leading to synergistic growth inhibition of cancer cells. Etoposide tumor protein p53 Homo sapiens