Pub. Date : 2020 Nov
PMID : 32777676
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Meanwhile, we found that emodin suppressed the activation of the Akt pathway in lungtissue of allergic mouse models. | Emodin | thymoma viral proto-oncogene 1 | Mus musculus |
| 2 | Additionally, we found that emodin inhibited cellular proliferation and Akt activation in a dose-dependent manner in vitro. | Emodin | thymoma viral proto-oncogene 1 | Mus musculus |
| 3 | These findings indicated that emodin alleviated ASMCs proliferation by inhibiting PI3K/Akt pathway in vivo and in vitro, which may provide a potential therapeutic option for airway smooth muscle remodeling in asthma. | Emodin | thymoma viral proto-oncogene 1 | Mus musculus |