Pub. Date : 2020 Aug
PMID : 32776811
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Treatment with tetrandrine increased rhodamine 123 retention, downregulated the mRNA and protein expression of MDR1 and RGS10, and upregulated expression of HTRA1 in Hep-2/v cells. | tetrandrine | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 2 | CONCLUSION: We showed that tetrandrine exerts anti-MDR activity in Hep-2/v cells, possibly by inhibiting MDR1 overexpression-mediated drug efflux and by altering expression of HTRA1 and RGS10. | tetrandrine | ATP binding cassette subfamily B member 1 | Homo sapiens |