Title : Nicotine Alleviates Cortical Neuronal Injury by Suppressing Neuroinflammation and Upregulating Neuronal PI3K-AKT Signaling in an Eclampsia-Like Seizure Model.

Pub. Date : 2020 Oct

PMID : 32767216






3 Functional Relationships(s)
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1 Nicotine Alleviates Cortical Neuronal Injury by Suppressing Neuroinflammation and Upregulating Neuronal PI3K-AKT Signaling in an Eclampsia-Like Seizure Model. Nicotine AKT serine/threonine kinase 1 Homo sapiens
2 Moreover, nicotine increased p-AKT levels and decreased cleaved caspase-3 levels in cortical neurons. Nicotine AKT serine/threonine kinase 1 Homo sapiens
3 Our results suggest that nicotine protects against neuronal injury in the cortex following eclampsia possibly by inhibiting neuroinflammation and activating neuronal PI3K-AKT pathway. Nicotine AKT serine/threonine kinase 1 Homo sapiens